Modelling hypercholesterolaemia in rats using high cholesterol diet
نویسندگان
چکیده
منابع مشابه
Rutin Attenuates Hepatotoxicity in High-Cholesterol-Diet-Fed Rats
Background and Objective. High-cholesterol diet (HCD) intends to increase the oxidative stress in liver tissues inducing hepatotoxicity. Rutin is a natural flavonoid (vitamin p) which is known to have antioxidative properties. The aim of the present study was to investigate the potential effects of Rutin on hypercholesterolemia-induced hepatotoxicity in rats. Materials and Methods. Male Wistar ...
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سابقه و هدف: هیپرکلسترولمی یکی از فاکتورهای خطر بیماری‌های قلبی ـ عروقی است و افزایش کلسترول خون سلامت عمومی را تحت تاثیر قرار داده و میزان مرگ و میر ناشی از بیماری‌های قلبی ـ عروقی را افزایش می‌دهد. تغذیه با رژیم پرکلسترول باعث افزایش میزان LDL و همچنین کاهش فعالیت گیرنده‌های LDL در کبد می‌شود. اکسیداسیون لیپوپروتئین موجود در دیواره عروق، باعث پیشرفت بیماری آتروسکلروز می‌شود. شواهد چندی حاکی ...
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Paliurus spina-christi Mill (Rhamnaceae) has been used in folk medicine as a hypocholesterolemic agent. In this study, the effect of total fruit extract on lowering lipid content of serum was investigated. Male rats were introduced streptozocin, subsequently fed with a high cholesterol diet and concomitantly treated with various doses of the extract. After 8 days, serum levels of cholesterol, t...
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The present study investigated the effect of starvation-refeeding status on cholesterol metabolism in rats fed a high-cholesterol diet or a cholesterol-free diet. Twenty male and 20 female Donryu rats (age 5 weeks) were fed a cholesterol-free diet for 14 days. Then the male and female rats were each divided into two groups: feeding and starvation-refeeding groups. The feeding groups were fed th...
متن کاملEffect of individual amino acids on plasma cholesterol level in rats fed a high cholesterol diet.
The effect of individual amino acids added to a cholesterol containing casein diet on the plasma cholesterol level of rats was systematically investigated with objective of confirming the possibility that specific amino acids are responsible for the regulation of plasma cholesterol level by dietary proteins. Half the amino acids tested were effective to some degree in influencing the plasma cho...
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ژورنال
عنوان ژورنال: International Journal of Experimental Pathology
سال: 2021
ISSN: 0959-9673,1365-2613
DOI: 10.1111/iep.12387